BHS guidelines for the treatment of marginal zone lymphomas
نویسنده
چکیده
12 Department of Haematology, Institut Jules Bordet (ULB), Brussels, Belgium Department of Haematology, Cliniques Universitaires St Luc, Brussels, Belgium Department of Haematology, Hôpital de Jolimont, Haine St Paul, Belgium Department of Haematology, Universitair Ziekenhuis, Gent, Belgium Department of Haematology, Universitair Ziekenhuis, Antwerp, Belgium Department of Haematology, Centre Hospitalier Universitaire, Liège, Belgium Department of Haematology, AZ St Jan, Brugge, Belgium Department of Haematology, Gasthuisberg, Leuven, Belgium.
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Splenic marginal zone lymphoma: villous, not necessarily villainous.
The article by Thieblemont and colleagues very nicely summarizes the key pathogenetic and diagnostic features and present treatment of splenic marginal zone lymphoma (SMZL). This histologic subtype of non-Hodgkin lymphoma has evolved from being an unrecognized entity in earlier classification systems (such as the Working Formulation[1]), to a provisional entity in the Revised European/American ...
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Marginal zone lymphomas of all types (nodal, splenic, and extranodal mucosa-associated lymphoid tissue [MALT]) may show plasmacytic differentiation. Distinguishing marginal zone lymphomas from other small B-cell lymphomas with plasmacytic differentiation, especially lymphoplasmacytic lymphoma, or from plasma cell neoplasms may be challenging. Marginal zone lymphomas with plasmacytic differentia...
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Marginal zone lymphomas are indolent B-cell lymphomas that originate from the marginal zone of B-cell follicles. For several subtypes, the initiation of disease appears to be a consequence of chronic infection and/ or inflammation. While the initial lymphoid hyperplasia is driven by physiologic antigenic stimulation, additional oncogenic events, such as chromosomal translocations leading to con...
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The association between hepatitis C virus (HCV) infection and B-cell non-Hodgkin's lymphomas (NHL) has been demonstrated by epidemiological studies, in particular in highly endemic geographical areas such as Italy, Japan, and southern parts of United States. In these countries, together with diffuse large B-cell lymphomas, marginal zone lymphomas are the histotypes most frequently associated wi...
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BACKGROUND The marginal zone is an anatomically distinct B-cell compartment of lymphoid tissue with an abundant antigenic influx. Among marginal zone-derived lymphomas the WHO classification listed, in addition to extranodal marginal zone B-cell lymphoma of MALT type, two other marginal zone B-cell neoplasms: splenic marginal zone B-cell lymphoma (+/- villous lymphocytes) and nodal marginal zon...
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